Essentials of Clinical Psychopharmacology

by ;
Edition: 2nd
Format: Paperback
Pub. Date: 2006-02-10
Publisher(s): Amer Psychiatric Pub Inc
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Summary

This new edition of Essentials of Clinical Psychopharmacologyis a synopsis and update of the most clinically relevant material from The American Psychiatric Publishing Textbook of Psychopharmacology, Third Edition. The Essentialsfocuses on the aspects of psychopharmacology directly related to clinical care and will appeal to psychiatry residents, primary care physicians, and others interested in a concise tutorial on clinical psychopharmacology. The book is organized around two major sections of the Textbook. The first section, Classes of Psychiatric Treatments, presents information by classes of drugs and greatly expands on the first edition of the textbook by focusing whole chapters on single drugs in the antidepressant, antipsychotic, and bipolar categories. For each drug within a class, data are reviewed on preclinical and clinical pharmacology, pharmacokinetics, indications, dosages, side effects and toxicology, and drug-drug interactions. Included are data on currently available drugs in the United States and medications that will almost certainly become available in the near future. The second section, Psychopharmacological Treatment, provides specific information about drug selection and prescription and reviews state-of-the-art therapeutic approaches to the treatment of patients with major psychiatric disorders. Also reviewed are pharmacotherapeutic approaches for special populations, such as children and adolescents, medically ill patients, and the elderly. Chapters are devoted to pharmacotherapy in special situations, such as during pregnancy and lactation and in psychiatric emergencies. This section provides the reader with specific information about drug selection and prescribing practices. In addition to the clinical focus of the Essentials, the authors have provided new information based on more recent literature available since publication of the Textbook. Included are updates on the effectiveness and availability of specific drugs and therapeutic approaches.

Author Biography

Alan F. Schatzberg, M.D., is Kenneth T. Norris, Jr., Professor and Chairman of the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine in Stanford, California.

Charles B. Nemeroff, M.D., Ph.D., is Reunette W. Harris Professor and Chairman fo the Department of Psychiatry and Behavioral Sciences at Emory University School of Medicine in Atlanta, Georgia.

Table of Contents

Contributors xiii
Introduction xix
PART I Classes of Psychiatric Treatments: Animal and Human Pharmacology
Jack M. Gorman, M.D., Dennis S. Charney, M.D.
Antidepressants and Anxiolytics
1 Tricyclic and Tetracyclic Drugs
5(26)
J. Craig Nelson, M.D.
2 Fluoxetine
31(16)
Jerrold F. Rosenbaum, M.D., Gary D. Tollefson, M.D., Ph.D.
3 Sertraline
47(12)
J. Jewel Shim, M.D., Kimberly A. Yonkers, M.D.
4 Paroxetine
59(30)
Keith D. Herr, M.D., Charles B. Nemeroff, M.D., Ph.D
5 Fluvoxamine
89(12)
Janet M. Fairbanks, M.D., Jack M. Gorman, M.D.
6 Citalopram and S-Citalopram
101(12)
Patrick H. Roseboom, Ph.D., Ned H. Kalin, M.D.
7 Monoamine Oxidase Inhibitors
113(14)
K. Ranga Rama Krishnan, M.D.
8 Trazodone and Nefazodone
127(10)
Robert N. Golden, M.D., Karon Dawkins, M.D., Linda Nicholas, M.D.
9 Bupropion
137(16)
David C. Rettew, M.D. James J. Hudziak, M.D.
10 Mirtazapine
153(6)
Benjamin H. Flores, M.D., Alan F. Schatzberg, M.D.
11 Venlafaxine
159(12)
Michael E. Thase, M.D., Diane M.E. Sloan, Pharm.D.
12 Duloxetine and Milnacipran
171(10)
John F. Greden, M.D.
13 Benzodiazepines
181(18)
Ashok Raj, M.D., David Sheehan, M.D., M.B.A.
14 Buspirone
199(12)
Philip T. Ninan, M.D., Siham Muntasser, M.D.
Antipsychotics
15 Classic Antipsychotic Medications
211(124)
John Wilkaitis, M.D., Teresa Mulvihill, M.D. Henry A. Nasrallah, M.D.
16 Clozapine
229(16)
Stephen R. Marder, M.D. Donna A. Wirshing, M.D.
17 Olanzapine
245(18)
S. Charles Schulz, M.D. Stephen Olson, M.D., Michael Kotlyar, Pharm.D.
18 Quetiapine
263(14)
David J. Printz, M.D. Jeffrey A. Lieberman, M.D.
19 Aripiprazole
277(8)
David J. Printz, M.D. Jeffrey A. Lieberman, M.D.
20 Risperidone
285(12)
Donald C. Goff, M.D.
21 Ziprasidone
297(10)
David Gordon Daniel, M.D., Laura F. Copeland, M.S., Carol Tamminga, M.D.
22 Drugs to Treat Extrapyramidal Side Effects
307(28)
Joseph K. Stanilla, M.D., George M. Simpson, M.D.
Drugs for Treatment of Bipolar Disorder
23 Lithium
335(92)
Marlene P. Freeman, M.D., Christopher Wiegand, M.D., Alan J. Gelenberg, M.D.
24 Valproate
355(12)
Charles L. Bowden, M.D.
25 Carbamazepine and Oxcarbazepine
367(28)
Terence A. Ketter, M.D., Po W. Wang, M.D., Robert M. Post, M.D.
26 Gabapentin
395(8)
Mark A. Frye, M.D.
27 Lamotrigine
403(10)
Joseph R. Calabrese, M.D., Melvin D. Shelton, M.D., Ph.D. Keming Gao, M.D., Ph.D. Prashant Gajwani, M.D., Omar Elhaj, M.D.
28 Topiramate
413(14)
Susan L. McElroy, M.D., Paul E. Keck Jr., M.D.
Other Agents
29 Sedative-Hypnotics
427(38)
Seiji Nishino, M.D., Ph.D., Kazuo Mishima, M.D., Ph.D. Emmanuel Mignot, M.D., Ph.D. William C. Dement, M.D., Ph.D.
30 Psychostimulants in Psychiatry: Amphetamine, Methylphenidate, and Modafinil
449(16)
Christos A. Ballas, M.D. Dwight L. Evans, M.D. David F. Dinges, Ph.D.
PART II Psychopharmacological Treatment
David L. Dunner, M.D.
31 Treatment of Depression
465(1)
Robert J. Boland, M.D., Martin B. Keller, M.D.
32 Treatment of Bipolar Disorder
479(1)
Paul E. Keck Jr., M.D., Susan L. McElroy, M.D.
33 Treatment of Schizophrenia
503(1)
Tsung-Ung W. Woo, M.D., Ph.D., Suzanna V. Zimmet, M.D., Joanne D. Wojcik, R.N., M.S., C.S., Carla M. Canuso, M.D., Alan I. Green, M.D.
34 Treatment of Anxiety Disorders
535(1)
Jonathan R.T. Davidson, M.D., Kathryn M. Connor, M.D.
35 Management of Noncognitive Symptoms of Dementia
557(1)
Larry E. Tune, M.D., Julie Rosenberg, M.P.H.
36 Treatment of Childhood and Adolescent Disorders
575(1)
Karen Dineen Wagner, M.D., Ph.D.
37 Treatment of Substance-Related Disorders
647(1)
James W. Cornish, M.D., Laura F. McNicholas, M.D., Ph.D. Charles P. O'Brien, M.D., Ph.D.
38 Treatment of Eating Disorders
669(1)
W. Stewart Agras, M.D.
39 Treatment of Agitation and Aggression in the Elderly
677(1)
Carl Salzman, M.D.
40 Treatment of Personality Disorders
689(1)
Daphne Simeon, M.D., Eric Hollander, M.D.
41 Psychiatric Emergencies
707(1)
Steven J. Garlow, M.D., Ph.D., David Purselle, M.D., Barbara D'Orio, M.D.
42 Treatment During Late Life
725(1)
Steven P. Roose, M.D., Bruce G. Pollock, M.D., Ph.D., F.R.C.P. D.P. Devanand, M.D.
43 Psychopharmacology During Pregnancy and Lactation
745(1)
D. Jeffrey Newport, M.D., M.S., M.Div., Zachary N. Stowe, M.D.
44 Treatment of Insomnia
775(1)
Martin Reite, M.D.
Index 795

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